REQUIRED TESTS: GENOME, NUTREVAL
If you do not have a suitable genome analysis through a CLIA certified lab (23 and me and My Heritage DNA are acceptable direct to consumer labs) or recent metabolomic testing, please contact NGI. Genome kits can be purchased and de-identified through NGI for $150 and the Nutreval can be ordered through NGI as well for $379.
Want to shave those extra minutes off of your next iron man? This is the panel for you! Find out how to optimize your muscle fibers and mitochondria for optimal speed and endurance.
In this panel we will look at the following genetics, along with your labs to help you navigate the best way for you to achieve your athletic goals.
Our client “Jenny” has run numerous marathons. She finds running meets her need for a “dopamine rush”. She has good motivation but finds herself not making the same gains as her training partners. She has sustained many injuries including stress fractures, ankle pain and an immediate inflammatory response after work outs. She finds herself taking a lot of Advil during training.
After running Jenny’s SportDx, we found that she has a higher prevalence of SNPs suited for strength or sprinting type exercise (i.e. a 5K) versus endurance (half and full marathons) which she had been doing. She has a high risk for injury which she had never taken into consideration when planning training schedules. In addition to that, she has risks for reactive oxygen species build-up and even an exercise induced heart attack without the appropriate antioxidant support! The goal is to empower athletes – thus, if she chooses to keep running long distances with her genetic profile she is now armed with knowledge that can help her improve her injury risk and hopefully marathon times! However, she might also consider working on shorter, higher intensity distances which her body may prefer!
Did you know in 2016 this first study to attempt to directly test whether genetic information could assist in training programs was published.
“Those undertaking genetically matched training—i.e., power-biased subjects undertaking power-biased training or endurance-biased subjects undertaking endurance-biased training—achieved around three times the magnitude of performance improvement in countermovement jump (CMJ) height and Aero3 tests.” PMID: 27274104
What determines Athletic performance?
• Muscle mass
• Production of energy (ATP)
• How you use glycogen
• Metabolic rate
• Average resting and max heart rate
• Lactate threshold
• Cardiac output
• Vo2 max response
• Muscle fiber type
• Skeletal muscle structure and function
• Fatigue resistance
• Training adaptation
• Injury resistance
• Respiratory system
• Psychological traits
• Exercise induced inflammatory risk
• Oxygen uptake
• Energy metabolism
• Blood pressure control
Questions to consider:
What training will you best respond to?
How well will you adapt to training?
When should you change the training stimulus?
How seriously should you take the risk of injury?
How quick will you recover?
How well will you respond to ergogenic aids?
Genes involved in athletic performance:
• Genes involved with your mitochondria “the powerhouse” of your cells.
o This is where we make energy! Those with impairment may present with more exercise intolerance. Learn how you can support these complexes that make energy in the SportDx.
• Genes that support strength and power sports.
o Do you have an advantage? Will carnosine, nitric oxide and glucose be more available to your muscles? Do you have slow or fast twitch muscles fibers? Do you have the rare myostatin gene variation that will result in extreme muscle size? Are you prone to exercise induced “air hunger?” Is your body better at delivering oxygen to your tissues? If you are like Jenny and want to run marathons but are more genetically at an advantage to be a sprinter what can you do?
• Genes that support endurance exercise.
o Is your body prone to hypertension? If so you need to be careful with endurance sports! How well does your body regulate its temperature (this may contribute to your experience with exercise!)? How does your body regulate blood flow during exercise (vasodilation) and can you improve this? Will you encounter more or less fatigue during exercise and how fast? Do you have less or more body fluid loss during exercise? How much skeletal muscle destruction occurs for you during exercise?
• Genes that influence your desire to work out.
o Do you need a dopamine rush like Jenny or if are you more prone to cruise the couch, what can you do about it?
• Genes that predict your injury risk and recovery need.
o How will your tendons, bones and ligaments respond to exercise? How well will you recover from traumatic brain injury (should you skip boxing and football?)
• Genes that predict how you will respond to ergogenic aids.
o Will caffeine benefit your race times?
• And much more!